Impact Biologicals Inc.

Proteins and Cell Lines for Biomedical Research

Our mission: to provide biomedical researchers with the proteins and cell lines they need in the fastest, most reliable manner possible.

Need

Biomedical researchers have a high and ever-increasing need for proteins and cell lines. This demand can stretch the capabilities of many organizations. As a contract manufacturer, Impact Biologicals allows its clients to do more by providing them with a highly-skilled outsourcing option to handle some or all of their protein and cell line production work.

Emphasis on Timeliness and Quality

Most proteins and cell lines can be produced quickly by judicious application of a small number of simple technologies. Impact Biologicals has selected and optimized a set of technologies--some proprietary, some not—that allow us to quickly solve 80-90% of the problems ordinarily encountered in protein and cell line generation. By operating these technologies in robust, SOP-driven formats, and by applying the right technology to the right problem, Impact Biologicals can satisfy its clients’ cell and protein needs quickly and with consistently high quality.

Core Technologies

It has been our experience that a few well-run technologies are sufficient for production of most proteins and cell lines. Accordingly, Impact Biologicals has emphasized the development of robust SOPs for these technologies:

■ Standard expression technologies in E. coli, including fermentation scale-up to 8 liters

■ Transient transfection of mammalian cells – often the fastest way to produce a few milligrams of protein or cell membrane to jump-start a research program.

■ Mammalian cell line generation.

■ Standard protein purification, typically involving affinity tags

Experience

Company founder and president Bernard Selling, Ph.D., has over 13 years of experience in the pharmaceutical industry, including seven years managing core groups responsible for protein and cell line generation at large pharmaceutical companies. These groups produced over 200 proteins and cell lines for a variety of applications including high-throughput screening, lead optimization, and structure-based drug design employing x-ray crystallography and NMR.

Contacting us

Impact Biologicals is located within easy reach of the Philadelphia biotech region, New Jersey pharmaceutical corridor, and research organizations throughout Delaware. Calls for information are always welcome.

Send an e-mail

Tel: (610)543-6320

Fax: (215)893-1738                             

info@impactbio.com

715 Harvard Avenue

Swarthmore, PA 19081

Proteins and Cell Lines for Biomedical Research